Uveitis is an inflammatory disease that damages the eye. It affects different parts of the eye, including the lens, retina, optic nerve, vitreous and the uvea, which includes the iris, ciliary body and choroid. It primarily affects people between the ages of 20 and 50, but it can occur at any age. It is a leading cause of vision loss in young adults and causes about 20 percent of legal blindness.
Each year, about 2 percent of the population is newly diagnosed with uveitis—a disease that takes various forms. It can be infectious or non-infectious. Your ophthalmologist will offer a more specific diagnosis, depending on where the disease is occurring in the eye.
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Uveitis may develop quickly, affecting one or both eyes.
- Light sensitivity
- Flashing lights
- Dark, floating spots (floaters)
- Eye pain or redness
- Blurred or decreased vision
- Narrowing of the pupils
If you experience any of these symptoms, please visit your ophthalmologist.
Anterior uveitis is the most common form, predominantly affecting young and middle-aged people. It causes eye redness and pain, blurred vision, light sensitivity and small pupils. It occurs in the front of the eye and is often associated with other inflammatory and infectious diseases. Eye drops are the main form of treatment.
Intermediate uveitis mostly affects young adults and occurs in the vitreous. Usually, it is not painful, but causes blurred vision and floaters. It is often associated with other diseases.
Posterior uveitis is the least common form of the disease. It occurs in the back of the eye, affecting the retina and the choroid.
Clinical trials are essential to the scientific process of developing new treatments: they test the viability and safety of experimental drugs and techniques, called “interventions,” on human beings. While there is no guarantee that enrolling in a clinical trial will provide any medical benefit, some patients do experience positive results after receiving an experimental therapy.
The website clinicaltrials.gov is a centralized database of clinical trials that are offered globally. But as the disclaimer on the site’s home page states, there is no guarantee that a listed trial has been evaluated or approved—the National Institutes of Health runs the site but does not vet its content. This means that there could be bogus or dangerous trials listed that are preying on patients. It is essential that you discuss a clinical trial with your ophthalmologist before enrolling, and that you pay close attention to enrollment criteria.
If you are interested in exploring what is available on the site you can click on the button below, which will take you to clinicaltrials.gov and initiate a search for trials relevant for patients living with Uveitis.
Four different kinds of medication are used to treat uveitis: cycloplegics, corticosteroids, immunosuppressive agents, and non-steroidal anti-inflammatory drugs (NSAIDs). These treatments work by eliminating inflammation, reducing pain, preventing tissue damage and restoring vision. These treatments involve different side effects, which you should discuss with your doctor. If left untreated, uveitis can cause lead to glaucoma, cataracts, and permanent vision loss. Download the printable fact sheet below for more detailed information about treatment options.
Uveitis Fact Sheet
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